Suzhou Foremed Legend Medical Technology Co., Ltd. ("Foremed Legend" for short) independently developed a new generation of intelligent cold air therapy device - Clean&Cool: refreshing healing wind, which adopts a new generation of intelligent cooling system, can effectively reduce the side effects of photoelectric treatment, improve the effect of medical beauty treatment and shorten the postoperative recovery period.

Cold Air Therapy Device

The cold air therapy device sprays cooling air onto the patient's treatment area, and reduces swelling, inflammation and muscle spasms, relieves pain, contusions and hematomas through low temperature stimulation. At the same time, it can reduce the metabolic rate and oxygen demand of the damaged surrounding tissues, thereby inhibiting the spread of the damaged area to the healthy area, avoiding secondary damage, and promoting tissue repair and wound healing to achieve therapeutic effects. It is widely used in the clinical medical field.

Principle of Cold Therapy

Based on the fact that after the skin is stimulated by cold, the signal is transmitted to the brain through nerves, and then transmitted to the hypothalamus by the brain, causing skin vasoconstriction, muscle tremor, and reduced sweat gland secretion, thereby reducing local congestion or bleeding, reducing the sensitivity of nerve endings, effectively relieving pain, reducing inflammation, and promoting physical recovery.

Product Advantages

Efficient Cooling

• With -40℃ dry air cooling system.

Intelligent cooling

• With built-in defrost-free function, maintenance is simpler;

• 5 pre-stored parameter modes, faster operation;

• It has 5 levels of cooling, 9 levels of wind speed and three parameter adjustments for treatment time to meet various clinical treatment needs.

Easy to operate

• 10.4-inch ultra-large touch screen, more convenient parameter adjustment;

• Equipped with universal hand tools, can be used with most mainstream optoelectronic equipment;

• Ultra-light hose with bracket design to reduce the dragging feeling of the hand during operation.

Rest assured service

• The instrument can work continuously for at least 12 hours, and all-day treatment is burden-free;

• 12-month warranty is burden-free;

• 365-day fast response, professional after-sales team escort throughout the process.

Practical application of cold air therapy device

Foremed Legend Clean&Cool cold air therapy device can be used in conjunction with a variety of optoelectronic devices to improve treatment effectiveness and patient comfort. Here are some common cases of combined use:

Laser equipment: including picosecond laser (Star Picosecond), long pulse laser (UP Bang Bomb), Q-switched laser, 2940 Erbium laser, CO2 laser, etc., used to treat pigmented skin, vascular lesions, wrinkles and other problems.

Intense Pulsed Light (Photon IPL): used for skin rejuvenation, red blood streak removal, brightening skin tone, etc., such as phototherapy miracle egg, M22, black gold, BB light, CC light.

Radio frequency equipment: including thermal lifting, monopolar radio frequency, bipolar radio frequency, multipolar radio frequency, fractional radio frequency, microneedle radio frequency, etc., to promote the reorganization and regeneration of collagen and tighten the skin.

Ultrasound equipment: such as high-energy focused ultrasound HIFU, used for facial lifting.

The combined use of these devices can achieve a balance between cold and heat, reduce the inevitable heating of surrounding skin tissue during photoelectric surgery, and thus reduce side effects such as pain, redness, swelling and pigmentation.

In addition to being used in conjunction with photoelectric devices, it can also be matched with injection operations to assist mesodermal hand acupuncture, microneedle injection, botulinum toxin injection, hyaluronic acid injection and hair transplant treatment.

Clinical application of cold air therapy device

(I) Study on the onset time of cold air replacing surface anesthesia

The low temperature of cold air can significantly reduce the skin nerve conduction velocity by affecting the exchange between Ca2+ and Na+ in nerve cells. For every 1℃ drop in skin temperature, the nerve conduction velocity will decrease by 0.4m/s. [2] How long does it take for the pain to disappear after cold air is applied to the skin? The study by Elif Sari et al. [3] provides the answer. In this study, they applied -28℃ cold air to the human body surface continuously, and used a 26G injection needle to apply pain stimulation to the test site every 10 seconds, and recorded the time it took for the needle prick pain to disappear after the cold air was applied. According to the experimental results, the time it took for the pain to disappear in women was 30-90 seconds, with an average of 52.88±1.6 seconds; the time it took for the pain to disappear in men was 30-90 seconds, with an average of 56.34±1.52 seconds; there was no significant difference between the two. From this experiment, it can be seen that continuous blowing of cold air can reduce epidermal pain until a painless effect similar to anesthesia is achieved, with a fast onset and no risk of sensitization, which can greatly improve the comfort during skin treatment.

(II) Application of cold air in laser treatment

1. Christian Raulin et al. [4] compared the pain and adverse reaction rates of cold air cooling and cold gel cooling in the process of using various lasers. The study covered long-pulse alexandrite laser, pulsed dye laser, and Q-switched laser. After comparison, 100% of the subjects said that they would prefer cold air as a facial epidermal cooling method; compared with gel, 63% of the patients had shorter duration of erythema after cold air cooling, 74% of the subjects had reduced erythema, 70% of the subjects had reduced purpura, and 83% of the subjects had reduced scabs; in addition, due to the reduction of pain and the risk of epidermal thermal damage, the energy of the treatment laser can be increased by 15%-30%. In this experiment, after blowing cold air at -15℃ for 8 seconds, the epidermal temperature can be reduced to 15℃, which significantly reduced the pain of treatment and the incidence of adverse reactions, and can be used as an effective auxiliary method for skin laser treatment.

2.Baerbel Greve et al. [5] compared the split surface with cold air cooling and without cooling during the pulse dye laser treatment of port wine stains. After continuous cold air blowing at -15℃ for 8 seconds, the epidermal temperature dropped to 15℃, and then the pulse dye laser treatment was performed. The results showed that 9 patients (69%) felt that laser treatment accompanied by cold air significantly reduced pain, and the incidence of adverse reactions such as purpura, erythema, edema, hypopigmentation, pigmentation, and scars in the cooling area was significantly reduced. Stefan Hammes et al. [6] also reached a similar conclusion. When pulse dye laser was used to treat facial telangiectasia, the pain score and purpura score were significantly reduced after using cold air cooling. It was most appropriate to reduce the epidermal temperature to 20℃. On the basis of not significantly affecting the vascular treatment effect, it improved the patient's comfort and reduced the occurrence of adverse reactions.

3. When using picosecond fractional laser to treat facial photoaging, cold air can also be used for analgesia. Zhou Chenxi et al. [7] confirmed this through experiments. Before picosecond fractional laser treatment, lidocaine cream was applied to one side of the face, and cold air was used to cool the other side. The results after laser treatment showed that the epidermal temperature on the cold air-cooled side was significantly lower than that of the contralateral lidocaine cream group during the operation and until 30 minutes after the operation. This significantly reduced the pain felt by the subjects during the operation, and the analgesic effect could be maintained after the operation, improving the experience.

(III) Application of cold air in injection treatment

Another application of cold air epidermal cooling in dermatology is to reduce pain in conjunction with injections. Falk G. Bechara et al. [8] and Firas Al-Qarqaz et al. [9] have conducted experiments on this use of cold air and reached similar conclusions. Using cold air for 1 minute before a single injection of botulinum toxin can reduce the pain score from 7.4 to 2.5 points, reducing the pain by 66.2%. This greatly reduces the discomfort of patients during injections and improves their tolerance.

References:

[1]Guillot X, Tordi N, Mourot L, et al. Cryotherapy in Inflammatory rheumatic diseases: a systematic review[J]. Expert review of clinical immunology, 2014, 10(2): 281-294.
[2]Algafly A A, George K P. The effect of cryotherapy on nerve conduction velocity, pain threshold and pain tolerance[J]. British journal of sports medicine, 2007, 41(6): 365-369.
[3]Sari E, Sandikci M M, Bakar B, et al. Estimated beginning time of local anesthesia effectiveness in forced cold air application: A preliminary study[J]. Journal of Cosmetic and Laser Therapy, 2016, 18(1): 22-24.
[4]Raulin C, Greve B, Hammes S. Cold air in laser therapy: first experiences with a new cooling system[J]. Lasers in Surgery and Medicine: The Official Journal of the American Society for Laser Medicine and Surgery, 2000, 27(5): 404-410.
[5]Greve B, Hammes S, Raulin C. The effect of cold air cooling on 585 nm pulsed dye laser treatment of port-wine stains[J]. Dermatologic surgery, 2001, 27(7): 633-636.
[6]Hammes S , Raulin C .Evaluation of different temperatures in cold air cooling with pulsed-dye laser treatment of facial telangiectasia[J].lasers in surgery & medicine, 2005, 36(2):136-140.
[7] Zhou Chenxi, Qin Xiaolei, Li Kai, et al. Safety and effectiveness of cold air cooling device in analgesia during 1064/532nm picosecond fractional laser therapy Observation[J]. Journal of Practical Dermatology, 2023, 16(03): 150-152+163.
[8]Bechara F G, Sand M, Altmeyer P, et al. Skin cooling for botulinum toxin A injection in patients with focal axillary hyperhidrosis: a prospective, randomized, controlled study[J]. Annals of plastic surgery, 2007, 58(3): 299-302.
[9]Al‐Qarqaz F, Al‐Aboosi M , Al-shiyab D, et al. Using cold air for reducing needle-injection pain[J]. International journal of dermatology, 2012, 51(7): 848-852.

Foremed Legend

The core founding team of Suzhou Foremed Legend Medical Technology Co., Ltd. comes from Peking University and other well-known universities at home and abroad. Foremed Legend Based on compliance and with product strength as the core, we focus on the design, development and application of high-end medical aesthetic optoelectronic equipment, and are committed to becoming a leading company in the field of high-end medical aesthetic optoelectronic equipment and a provider of integrated diagnosis and treatment intelligent solutions. , and the pioneer of medical beauty data integration platform.

Through the development of a series of key underlying technologies, Foremed Legend has independently developed picosecond laser therapy devices, long pulse laser therapy devices, and intense pulsed light therapy devices. We have developed a variety of high-end medical equipment, including skin detection devices, photoacoustic imaging skin detection devices, and cold air therapy devices, and continue to deepen the research and development of core product technologies, using better technical solutions to benefit the vast number of beauty seekers.

Adhering to the principle of using technology for good, Foremed Legend will work with industry and ecosystem partners to bring more safe and effective medical aesthetic optoelectronic equipment and integrated diagnosis and treatment solutions to the global medical aesthetic market.